Alba Guarné

Domaines de recherche

• Structural and biochemical studies of proteins, protein-protein and protein-DNA complexes involved in DNA damage signaling and repair, and DNA transposition.

Projets de recherche en cours

• Mechanisms of Tn7 and Tn6022 targeting.
• Structure-selective nucleases in DNA repair.
• Lesion bypass polymerases.
• Allosteric activation of TNAP.
• DNA nanostructures.

Outils et expertises

• X-ray crystallography, Small-angle X-ray scattering, cryo-electron microscopy (single-particle analysis), biochemistry, biophysics, DNA repair, DNA transposition, protein-DNA interactions, transient protein interactions, structure-selective nucleases.