Marc Lussier

Research Interests

• E3 protein ligases of the ubiquitin system
• Post-translational modifications of proteins
• Intracellular dynamics of membrane proteins

Current Research Projects

• The interplay between ubiquitin and phosphorylation systems
• Impact of protein ubiquitin E3 ligases on the endolysosomal system
• Contribution of protein variants in developmental and epileptic encephalopathy

Tools and Expertises

• Protein-protein interaction analysis by Alphascreen
• In vitro/in-cell assays (ubiquitination and phosphorylation)
• Primary neuronal culture (hippocampus and cortex, rat and mouse)
• Total internal reflection fluorescence microscopy