Jean-Philippe Lambert

Research Interests

• Chromatin
• Epigenetics
• Protein acetylation
• Proteomics
• Mass spectrometry

Current Research Projects

• Characterization of the bromodomain-dependent interactions involved in the transcription cycle
• Analysis of the molecular mechanisms leading to bromodomain inhibitors resistance.
• Study of the acyl-CoA metabolic pathways and of their impact on the epigenomes.

Tools and Expertises

• Protein interaction mapping by affinity purification and proximity dependent biotinylation.
• Functional and quantitative proteomics of protein complexes
• Identification of post-translational modifications.