Research Interests
- Proteogenomics, discovery of new proteins.
- Customized protein databases, functionnal annotation of genomes.
- Alternative protein-coding sequences and microproteins.
Current Research Projects
Two main research axes :
- Discovery of new proteins (alternative proteins, microproteins) encoded in the genome with the OpenProt proteogenomics ressource, and functional characterization, protein misfolding and neurodegeneration.
- Improve the annotation of the coding potential of genomes. Multicoding and polycistronic genes.
Tools and Expertises
- Proteogenomics, functional proteogenomics, customized protein databases from RNAseq data, high resolution microscopy, cell biology, prion diseases.