Yves Durocher

Research Interests

  • Expression de protéines recombinantes en cellules de mammifères
  • Développement de lignées stables CHO pour la biofabrication

Current Research Projects

  • Transient gene expression in HEK293 and CHO cells for r-protein production.
  • Production and purification of recombinant monoclonal antibodies.
  • Stable CHO pool development for recombinant protein production.
  • Stable CHO cell line development for Biomanufacturing.
  • Subunit and virus-like particles vaccine development.
  • Cell engineering for improving r-protein glycosylation.

Tools and Expertises

  • HEK293 and CHO cell culture in suspension and serum-free medium
  • molecular biology
  • CRISPR/Cas9
  • large-scale production and purification of r-proteins and plasmid DNA
  • flow cytometry
  • bioreactors

Our scientific teams