David Chatenet

Research Interests

• G protein-coupled receptor pharmacology
• Peptide Engineering
• Design of biased and/or allosteric ligands
• G protein-coupled receptor pharmacology oligomerization

Current Research Projects

• Study of the therapeutic potential and the pharmacological complexity of the urotensinergic system
• Development of non-peptide allosteric modulators of the urotensinergic system
• Design and analysis of Signal-Regulatory Protein Alpha derivatives on inflammatory responses mediated by different viruses
• Development of Contulakin-G analogues for pain treatment
• Development of pepducins derived from the angiotensin II type I receptor

Tools and Expertises

• Liquid and solid phase peptide synthesis
• Organic chemistry
• Mass spectrometry
• Cell culture (study of cell signaling using fluorescent or bioluminescent biosensors)