Yves Durocher

Research Interests

• Expression de protéines recombinantes en cellules de mammifères
• Développement de lignées stables CHO pour la biofabrication

Current Research Projects

• Transient gene expression in HEK293 and CHO cells for r-protein production.
• Production and purification of recombinant monoclonal antibodies.
• Stable CHO pool development for recombinant protein production.
• Stable CHO cell line development for Biomanufacturing.
• Subunit and virus-like particles vaccine development.
• Cell engineering for improving r-protein glycosylation.

Tools and Expertises

• HEK293 and CHO cell culture in suspension and serum-free medium
• molecular biology
• CRISPR/Cas9
• large-scale production and purification of r-proteins and plasmid DNA
• flow cytometry
• bioreactors